Both do look similar, and both can be delicious as part of a sandwich or in a salad. Many people choose to use either meat as part of a topping on a pizza. Both serrano ham and prosciutto are made from meat from white pigs, and both are dry-cured. Both also have a salty texture and are very thinly sliced.
Serrano is a dry-cured ham, and that goes back to its origins. Back then, serrano was prepared in the mountains, where the climate frequently changed from dry and hot to cold and moist, and that created a gradual aging process that continues until this day.
The word prosciutto literally translates to “ham” in Italian, and it is primarily made in Italy, but it is also made around the world. Like deli ham, prosciutto can be both cooked and eaten raw, and it’s delicious either way.